Dr. Md. Rashidul Hasan

Relation of Antinuclear Antibody in Polymorphic Light Eruption

Background: Polymorphic light eruption (PLE) is a very common photosensitive disorder worldwide where elevated titers of antinuclear antibodies (ANA) were found in PLE patients.

Objective: In this study, our main aim is to detect whether ANA positivity is associated with an increased
risk for development of PLE.

Methodology: This cross-sectional study was done at US Bangla Medical College and Hospital and
different private chambers in Dhaka district from two years January 2018–to July 2019 among 100 patients.
Consent was taken from all the patients before their inclusion into the study. Our study consisted of 50
patients and 50 healthy age and gender-matched controls who attended the outpatient Department of
Dermatology, STD, and Leprosy an associated hospital of Dhaka. An automatic immunoassay analyzer (ELISA test) was done to measure the ANA index.

Result: During the experiment, most of the patients belongs to 31-40 years age group, and the male percentage (80%) was higher than the female. Also, in case of group, only 7% show ANA positivity whereas in the control group 2% of patients show ANA positivity.

Conclusion: from our result, we can conclude that there was very little difference in the ANA positivity
rate between cases and controls and also of the levels of ANA with the severity of the disease. Long-term
follow-up of the patients is being undertaken to describe more fully the disease course and prognosis.

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